皮質形成異常を伴った高齢発症てんかんの1例

Late Onset Epilepsy Associated with Migration Disorder：A Case Report

症例は57歳女性。一点凝視症，口部自動症が頻回に起きるようになったため精査を行ったところ，脳波で右蝶形骨誘導に棘波，頭部MRIで右側頭葉内側部に皮質形成異常と思われる所見を認めた。皮質形成異常に伴う内側型側頭葉てんかんとして薬物治療を開始したところ，発作は消失した。皮質形成異常に伴う50歳以降発症のてんかん発作は報告がなく，稀な症例と思われた。

We reported a 57-year-old female patient recently suffering from frequent seizures such as motionless staring and oral automatism.Electroencephalograms showed spikes in the right sphenoidal derivation and magnetic resonance images revealed an abnormal region, most likely related with a migration disorder such as a focal cortical dysplasia.She was diagnosed as mesiotemporal lobe epilepsy associated with a migration disorder.Seizure disappeared after medication therapy was done.No previous literature has described such a case, thus this is the first report of an epilepsy associated with migration disorder newly onset in a patient older than 50 years old.