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Usefulness of the Side-effect Check Sheet for Patients Taking Psychotropic Drugs Akiyoshi KIKKAWA 1 , Ken WADA 2 , Akiko YASUNAGA 1 , Miwa WATANABE 1 , Kouichi HIRAKI 1 1Department of Pharmacy, Hiroshima City Hospital, Hiroshima, Japan 2Department of Psychiatry, Hiroshima City Hospital Keyword: Side effect , Check sheet , Psychotropic drug , Mood disorder , Adherence pp.177-184
Published Date 2013/2/15
DOI https://doi.org/10.11477/mf.1405102388
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 The incidence of adverse drug reactions in patients receiving psychotropic drugs significantly affects drug adherence. Generally, side-effect monitoring for hospitalized patients is performed by interview. However, such evaluations are not considered sufficient because of time constraints and lack of patient understanding. In the present study, we introduced a self-descriptive side-effect check sheet consisting of 17 items and investigated the incidence and degree of severity of adverse drug reactions. The participants were 103 patients who provided written consent. Each patient was asked to respond to the survey after approximately 1 week of hospitalization. Their answers were confirmed when the sheet was collected, with the side-effects of vision disturbance, diarrhea, palpitation, decreased libido, and menstrual irregularity confirmed only via the sheet survey. Overall, the incidence of adverse drug reactions confirmed via the sheet survey was 10 times greater than that noted by interview alone. The severity of digestive symptoms, such as gastrointestinal disorders, diarrhea, nausea, and constipation, in descending order of prevalence, were ranked high in the evaluations. Our results suggest that the use of a check sheet for hospitalized patients enabls confirmation of adverse drug effects that are not fully identified by interview and provides a more detailed evaluation.


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電子版ISSN 1882-126X 印刷版ISSN 0488-1281 医学書院

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