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A Case of Superior Mesenteric Artery Thrombosis in a Patient with Anti-Cardiolipin-Antibody Syndrome associated with Systemic Lupus Erythematosus Masaharu Nagayama 1 , Kenichi Koyano 2 , Syukichi Sakaguchi 2 , Kingo Chida 3 1Department of Internal Medicine, Hamaoka Municipal Hospital 2Department of Surgery, Hamaoka Municipal Hospital 3Second Department of Internal Medicine, Hamamatsu University, School of Medicine Keyword: 全身性エリテマトーデス , 抗リン脂質抗体症候群 , 上腸間膜動脈血栓症 , systemic lupus erythematosus , antiphos pholipid antibody syndrome , thrombosis of superior mesenteric artery pp.821-825
Published Date 1998/8/15
DOI https://doi.org/10.11477/mf.1404901748
  • Abstract
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A 45-year-old man, who had been followed up as case of Systemic Lupus Erythematosus (SLE) for 4 years. was admitted to our hospital because of fever, abdominal pain and diarrhea. He had been treated with corticoster-oid therapy and the close of predonisolone (PSL) had been decreased from 10mg to 7. 5 mg every other day bout one month before admission. Laboratory findings owed that the SLE was in the active stage, we suspect-ed vasculitis of the small or large intestine. Conserva-tive treatment with increasing PSL close up to 60mg/ day, however, was not effective, and laparotomy was performed because CT examination confirmed perfora-tion of the intestine. Thrombosis of the superior mesentric artery (SMA) and necroses in the entire small intestine were found. Although vasculitis was detected in small vessels within the mesenterium, there was neither arteriosclerosis nor vasculitis in the SMA wall.We found that anti-cardiolipin β2 glycoprotein I com-plex antibody was positive, so we diagnosed this case as anti-cardiolipin-antibody syndrome with SLE.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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