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老年者本態性高血圧症入院患者23名(男5,女18,81.8±6.8歳)を対象とし,7g/日減塩食8週間後,20g/日増塩食3週間の各最終日に,超音波パルス・ドプラー法を用いて,心拍出量,総末梢血管抵抗を算出し,拡張期左室流入動態を解析した.
1)減塩期に比較して増塩期の平均血圧上昇10%以上を食塩感受性(SS)群19名,10%未満を食塩非感受性(NSS)群4名とし,更にSS群を心拍出量依存(SSC)群5名と,総末梢血管抵抗依存(SST)群14名とに分類した.
Three-week effects of a high sodium diet on mitral flow pattern were assessed in 23 patients with essential hypertension (81.8±6.8 years). Transmitral flow was recorded during different rates of salt intake : 7 g/day for 8 weeks, 20 g/day for 3 weeks. With sodium load-ing, 19 patients whose mean blood pressure (MBP) in creased by 10 percent or more were termed the salt-sensitive (SS) group, and 4 patients whose MBP did not change, or increased by less than 10 percent were termed the non salt-sensitive (NSS) group. With mitral veloc-ity integral, cardiac output (CO) and total peripheral resistance (TPR) were calculated.
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