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Clinical Study of Ten Cases with Deep Vein Thrombosis of Lower Limbs Sachiko Tonooka 1 , Norimichi Koitabashi 1 , Takuji Toyama 1 , Shigeki Sakurai 1 , Sanae Shimaya 2 , Satoru Arita 3 , Kouichi Taniguchi 3 1Division of Internal Medicine, Gunma Prefectural Cardiovascular Center 2Division of Radiology, Gunma Prefectural Cardiovascular Center 3Division of Orthopaedic Surgery, Gunma Prefectural Cardiovascular Center Keyword: 下肢静脈血栓症 , ヘパリン投与量 , 整形外科手術 , deep vein thrombosis , heparin dose , orthopedic surgery pp.291-294
Published Date 1998/3/15
DOI https://doi.org/10.11477/mf.1404900069
  • Abstract
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Deep vein thrombosis (DVT) is a major cause of pul-monary thromboembolism (PTE). Patients with DVT, however, will be relieved from risks of PTE by sufficient and effective initial management. The aim of this paper is to compare therapeutic modes for DVT among our ten cases of patients with DVT and those recorded in the American Heart Association (AHA) statement. Methods: We analysed ages, genders, periods of symp-toms to previous diagnosis, BMI, loading dose of warfar-in, bolus heparin, heparin maitenance dose, periods of heparinization, overlapping days of heparin and warfar-in administration and periods of hospitalization in ten cases of patients with DVT. Results : Subjects (Mean age 52.7 years, five males and five females) were divided into five patients of the non-heparinized warfarin ther-apy group and five patients of the overlapping heparin-warfarin group. It took twenty four days to finally diagnose the patients into these two groups. Basic dis-eases of the patients were hyperlipidemia, arithropaty, osteosarcoma, uterine myoma, fracture of the femoral neck, dilated cardiomyopathy, Raynaud's syndrome and polycystic kidneys. Three out of ten patients developed the DVT after orthopedic surgery. Increased BMI sug-gests that fatty people may be prone to develop DVT. Among our patients, bolus (2000IU vs 5000IU) and maitenance (580 IC vs 1333IU) dosages of heparin were much lower and heparinization and hospitalization periods were longer, compared with those recorded in the AHA-statement. Conclusion : The characteristics in our ten cases could be made, extensive delay until accurate diagnosis, lower dosage of heparin, longer heparinization and hospitalization. Early and adequate management of DVT is indispensable for the prevention of PTE.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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