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日常診療上,外来患者の血圧日内変動を調べることは容易でなく,とくに睡眠中の血圧測定は困難なものである。最近,数種類の非観血的携帯型カフ付24時間自動血圧計が開発され,普及しつつあるが,カフ加圧による上腕部の突然な圧迫が外来患者の自宅の寝床における睡眠に及ぼす影響については誰にも睡眠障害を引き起こすであろうと思われているがいまだ実証されてはいない。この自動血圧計による睡眠への影響を把握しておくことは今後の血圧日内変動の研究に際して非常に役立つものと思われる。そこで,著者らは睡眠時無呼吸症候群診断の簡便化のために開発した睡眠ホルター法(携帯型8チャンネルポリグラフィ)1,2)——本法は被検者の自宅の寝床において従来の睡眠ポリグラフィ(polysomnogra—phy)3)とほぼ同等の記録が無拘束化に施行でき,睡眠状態を比較的容易に客観的に評価可能である——を用いて,非観血的携帯型上腕カフ付自動血圧計による睡眠中の血圧測定時に実際に睡眠障害が生じるか否かを検討した。
Examining circadian rhythm of arterial blood pres-sure (BP) in out-patients is not easy. Particularly measuring BP during sleep is difficult. Recently, several kinds of non-invasive ambulatory 24-hour automatic sphygmomanometer (NAAS) fitted with a cuff have been developed. However, it has not been known whether or not the disturbance of sleeping is caused by cuff-pressure applied to the upper arm for measurement of BP with them. Therefore, we studied the usefulness of measuring BP during sleep by means of a NAAS.
The subjects were seven normal males aged 25-35 years. Recording of ambulatory polygraphy (sle-eping Holter's monitoring system ; Sleep Holter) was taken in the bed of their homes from evening to morning of the following day for two nights. The first night was used as the control. During the second night, a NAAS was fitted to the subjects and a comparative study was performed to clarify the effect of the cuff-pressure applied every 30 minutes at night on the sleeping. Sleep Holter comprises inputting EEG, EOG, EMG, ventilation curves for the nose, respiratory movement curves for the thorax and ECG simultaneously into the Oxford Co. -made Medilog 9000 devised as an 8-channel Holter's EEG. NAAS used in this study was Nippon Korin Co. -made ABPM-630.
During automatic measurement of BP, only one of 7 subjects complained of interruption of sleep. However, the effect on the sleep pattern was in-significant. The results of this study suggested the usefulness of NAAS with a cuff as the non-invasive method for measuring BP during sleep.
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