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Left ventricular function prior to and after transluminal coronary angioplasty (TCA) Nariaki Kanemoto 1,2 , Hör, G , Kober, G. pp.805-810
Published Date 1984/8/15
DOI https://doi.org/10.11477/mf.1404204493
  • Abstract
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The effect of TCA upon left ventricular func-tion and exercise capacity was studied non-inva-sively using exercise electrocardiography (ExECG) and radionuclide ventriculography (RNVG) in 48 patients with coronary artery disease. These patients were divided into three groups. Group 1, 28 patients (mean age 49) with successful TCA : group 2,6 patients (mean age 48) who underwent aorto-coronary bypass surgery (AC-BS) because of unsuccessful TCA : group 3, total of 15 patients including 5 patients with unsuccessful TCA for the control study. Twelve patients with successful TCA reevaluated after 3 months.

ExECG and Tl-201 myocardial scintigraphy (TMS) using arm-assisted step test were done 3-5 days prior to and after scheduled TCA: as to the group 2 patients within 5 months after AC-BS. Parameters obtained were duration of exercise, left ventricular ejection fraction (EF), mean systolic ejection rate (MSER), max dC/dt/ED and max dC/dt/ES.

In group 1, luminal diameter of coronary artery stenosis before TCA 83.6±7.5% was dilated to 43±14.5% (p<0.001). EF both at rest and during exercise increased significantly from 46.8± 9.5% and 39.6±10.7% to 51.9±9.4% and 49.4±10.9%, respectively (each p<0.001) following TCA. Other parameters showing left ventricular myocar-dial function increased significantly after the procedure. However, no changes were noted in these parameters in group 3.

These short time results suggest TCA improves coronary perfusion to ischemic areas supplied by critical coronary artery stenosis and hence increases left ventricular function especially during exercise.


Copyright © 1984, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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