マルチゲート心プール法位相解析よりみた心室内伝導障害例の検討

Quantltative evaluation of the cardiac blood pool study in patients with intraventricular conduction abnormalities

　Green^1）らによる心電図同期ラジオアイソトープ心プール・イメージ法（マルチゲート法）が開発^2）されて以来，心室機能解析の発達はめざましい。1978年Adam^3）らにより導入されたマルチゲート法で得られるデータを基にして行う位相解析は，局所心室壁の収縮を空間的（振幅），時間的（位相）にとらえる方法として注目されている。

　今回，著者らは種々の心室内伝導障害を有する9症例を対象にマルチゲート法位相解析を行い，臨床面における有用性を検討したので報告する。

Quantitative evaluation of ventricular contrac-tion abnormality by gated blood pool study was at-tempted using temporal Fourier analysis (phase analysis). The value of the left ventricular ejectionfraction (LVEF), ejection rate and the standard deviation (SD) of the phase distribution histogram were clinically evaluated.

Five normal persons and 9 patients with intraven-tricular conduction abnormalities were selected for gated blood pool study. In all of the normal subjects and WP\V syndrome, the SD was within 10 degree and the phase distrubition histogram showed nor-mal findings. On the contrary, in the patients with intraventricular conduction abnormalities such as CLBBB, LAD & CRBBB and pace-maker implanta-tion, the SD was significantly elevated and the phase distribution histogram indicated asynchrony.

We concluded that phase analysis provides relia-ble and valuable informations in the detection of ventricular contraction abnormality in the patients with intraventrucular conduction abnormalities.