Coronary Artery Disease in Heterozygous Familial Hypercholesterolemia Kazuhiko Hirobe 1 , Hiroshi Hara 1 , Kaoru Kameda 1 , Katsuto Tokunaga 1 , Masaharu Kubo 1 , Hiroshi Sudo 1 , Yuji Matsuzawa 1 , Katsunori Ishikawa 1 , Seiichrou Tarui 1 , Akira Yamamoto 2 , Seiki Nanbu 2 , Kiyoshi Fujimoto 3 12nd Department of Internal Medicine, Osaka Univ. Med. School 2Department of Pathological Science and Department of Hedicine, Research Institute, National Cardiovascular Center 3The Department of Circulatory Dynamics, The Center for Adult Disease, Osaka pp.87-93
Published Date 1982/1/15
DOI https://doi.org/10.11477/mf.1404203917
  • Abstract
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Coronary artery disease (CAD) is a common complication of Familial Hypercholesterolemia (FH), but some patients are not associated with CAD even if their serum cholesterol levels are high enough and are at old age. The purpose of this study is to define the relationship between the prevalence of CAD and the lipoproteins abnormalities and Achilles tendon thickness in FH patients considering age and sex.

51 heterozygous FH patients were devided into two groups, that were patients with CAD and without CAD. The levels of total cholesterol (TC), HDL-cholesterol (HDL-C), triglyceride (TG), Atherogenic Index (AI) and Achilles tendon thickness (ATT) were detected and compaired between each other.

Copyright © 1982, Igaku-Shoin Ltd. All rights reserved.


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