慢性肺気腫における肺胞気の検討

Studies on Alveolar Air in Chronic Pulmonary Emphysema

緒言

　慢性肺気腫のガス及び血液動態に関してはSe—agal^1），　Motley^2），村尾^{3），4），5）}，横山^6）等により既に多数報ぜられている。元来肺の機能は気相及び血液相との間におけるO₂とCO₂のガス交換が主である。然も血液相は動脈血によつて或程度代表され得るので気相及び動脈血の各検査成績を求めることによつて相当正確な肺機能障害の成績が求め得るわけである。著者はこの中CO₂を主体とし，各種肺機能検査の一環としてListon—Becker社製Model 16CO₂メーターを使用して得られた検査成績を中心として述べる。

Studies on alveolar air in 80 patients with chronic pulmonary emphysema were performed by use of Liston-Becker continuous CO₂ analyzer. Arterial blood CO₂ tension was similarly examined in 59 cases among the total. In the previous days alveolar functions were studied on the basis of the theory of alveolar equation, which reveals that the CO₂ tensions of alveolar air equals to that of arterial blood in steady state. But in pulmonary emphysema we could make it clear by continuously analyzing CO₂ gas concentration in the expired gas that the inhaled air, even most diffusible CO₂ gas, was unevenly distributed in the emphysematous lung tissues. It is, however, necessary to recall that these relations between uneven CO₂ distribution and the factors of functional disability of the lung has been also evaluated from the so-called "Ideal Alveolar Equation", and hence these probelms should be resolved in the future studies.