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Amrubicin Hydrochloride Chemotherapy for Small Lung Cell Carcinoma with Chronic Renal Failure Undergoing Hemodialysis Kohsyu Ohkubo 1 , Hidefumi Koh 1 , Ichiro Nakachi 2 , Kentaro Fujii 1 , Akihiko Sudoh 1 , Hidenori Takahashi 1 , Atsushi Chiyotani 1 , Atsushi Tajima 3 , Yasuhiro Ohkubo 4 , Makio Mukai 5 1Division of Pulmonary Medicine, Department of Internal Medicine, Saiseikai Utsunomiya Hospital 2Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine 3Department of General Thoracic Surgery, Saiseikai Utsunomiya Hospital 4Division of Nephrology, Department of Internal Medicine, Saiseikai Utsunomiya Hospital 5Department of Pathology, Keio University School of Medicine Keyword: 肺小細胞癌 , 慢性腎不全 , 塩酸アムルビシン , small cell lung carcinoma , chronic renal failure , amrubicin hydrochloride pp.547-551
Published Date 2012/5/15
DOI https://doi.org/10.11477/mf.1404101966
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 A 79-year old man who had undergone hemodialysis for 4 years visited our hospital because of pulmonary abnormal shadow. He was diagnosed as having extensive small cell lung carcinoma based on further examination and treated with Amrubicin hydrochloride on day 1 to 3 of each 28 day therapy course. Four courses of chemotherapy resulted in remarkable reduction of the tumor. Finally he completed 6 courses of Amrubicin. No severe side effects were observed except grade 2 of anemia. He did not receive G-CSF and blood transfusion. It has been reported that Etoposide and Irinotecan were effective for small cell lung carcinoma complicated with chronic renal failure undergoing hemodialysis, but there have been few reports on Amrubicin. Although further research will be needed, Amrubicin may be effective for small lung cell carcinoma with chronic renal failure undergoing hemodialysis.


Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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