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Four Cases of Jejunal and Ileal Cancer with Familial Adenomatous Polyposis Tetsuya Ito 1 , Hideyuki Ishida 1 1Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan Keyword: 空腸癌 , 回腸癌 , 家族性大腸腺腫症 , APC遺伝子 , デスモイド腫瘍 pp.829-836
Published Date 2022/5/25
DOI https://doi.org/10.11477/mf.1403202918
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 FAP(familial adenomatous polyposis)is an autosomal dominant inherited disease in which patients develop colorectal cancer and various associated lesions. Among the 151 cases of FAP in our department ; here, we present four cases of jejunal and ileal cancer:one case of jejunal cancer and three cases of ileal cancer, with two of the ileal cancer cases occurring at the colostomy site. Our analysis shows that the lifetime risk(at 70 years of age)of developing jejunal and ileal cancer is 15.7%. However, because appropriate surgical treatment for FAP and advances in surveillance can reduce the number of deaths due to colorectal cancer at a young age, the incidence of jejunal and ileal cancer may increase in the future. Therefore, we hope that a carcinogenic mechanism will be elucidated and that surveillance will be established by the accumulation of cases.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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