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Japanese

Significance of Assessing Mucosal Healing in Ulcerative Colitis Using Conventional Colonoscopy with White Light Imaging Makoto Naganuma 1 , Norimasa Fukata 1 , Yasuki Sano 1 , Shuhei Nishimon 1 , Takashi Tomiyama 1 , Toshiro Fukui 1 1Third Department of Internal Medicine, Kansai Medical University, Hirakata, Japan Keyword: 潰瘍性大腸炎 , 白色光内視鏡 , Mayo内視鏡スコア , 内視鏡的寛解 , 粘膜治癒 pp.132-140
Published Date 2022/2/25
DOI https://doi.org/10.11477/mf.1403202653
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 In recent years, mucosal healing or endoscopic remission has been set as the therapeutic target for UC(ulcerative colitis). Endoscopic evaluation with white light imaging is the standard modality for treating UC and can be performed at any facility. MES(Mayo endoscopic score)objectively evaluates the degree of endoscopic activity. Previously, an MES of 1 or less was considered as endoscopic remission(mucosal healing). However, more recently, an MES of 0 has been defined as endoscopic remission based on long-term prognosis. While the objective of endoscopic evaluation is to estimate the clinical risk of UC and provide appropriate medical treatment to patients in case of clinical remission, it is critical to consider the time elapsed from therapeutic intervention to endoscopic evaluation while assessing remission. Furthermore, once endoscopic remission is confirmed, it may be worthwhile to reduce or even discontinue medical treatments. In future, an MES of 0 may be subdivided into categories based on histological activity and prognosis.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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