Stomach and Intestine(Tokyo) Volume 53, Issue 13 (December 2018)
Japanese

Contrast-enhanced Harmonic EUS for Differential Diagnosis of Submucosal Tumors Ken Kamata 1 , Mamoru Takenaka 1 , Rei Ishikawa 1 , Chie Yoshikawa 1 , Ayana Okamoto 1 , Tomohiro Yamazaki 1 , Atsushi Nakai 1 , Shunsuke Omoto 1 , Kosuke Minaga 1 , Kentaro Yamao 1 , Toshiharu Sakurai 1 , Shigenaga Matsui 1 , Tomohiro Watanabe 1 , Naoshi Nishida 1 , Hiroshi Kashida 1 , Masatoshi Kudo 1 1Department of Gastroenterology and Hepatology, Kinki University, Osakasayama, Japan Keyword: EUS , 造影ハーモニックEUS , GIST , 消化管粘膜下腫瘍 , 胃粘膜下腫瘍 pp.1795-1799
Published Date 2018/12/25
DOI https://doi.org/10.11477/mf.1403201545
  • Abstract
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 EUS(endoscopic ultrasonography)is a diagnostic method with a high sensitivity for detecting subepithelial tumors ; however, it is generally difficult to distinguish between benign and malignant disease using conventional EUS. One prospective study and six retrospective studies have reported the usefulness of CH-EUS(contrast-enhanced harmonic EUS)for the characterization of subepithelial lesions in the upper digestive tract. Three studies have investigated the use of CH-EUS for distinguishing between GISTs and the subepithelial lesions in the upper digestive tract. These reports showed that hyper-enhancement was a sign of GIST, sensitivity ranged from 84.5% to 100%, and specificity ranged from 73.3% to 100% for the diagnosis of GISTs. Four studies have reported on CH-EUS for distinguishing between low-grade malignancy and high-grade malignancy GISTs. These reports showed that the sensitivity ranged from 53.8% to 100%, and specificity ranged from 63% to 100% for the diagnosis of high-grade malignancy GISTs. Among these, three reports showed that irregular(or intratumoral)vessels were a sign of high-grade malignancy GISTs. These studies that used CH-EUS for the characterization of subepithelial lesions in the upper digestive tract enrolled a small number of patients ; therefore, further studies are warranted.


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基本情報

05362180.53.13.jpg
胃と腸
53巻13号 (2018年12月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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