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Magnified Endoscopic Findings which Suggest Inflammation in Superficial Esophageal Squamous Cell Carcinoma:A New Sub-classification of B2 i Akiko Takahashi 1 , Tsuneo Oyama 1 , Nobukazu Yorimitsu 1 1Department of Endoscopy, Saku Central Hospital Advanced Care Center, Saku, Japan Keyword: 食道扁平上皮癌 , 拡大内視鏡分類 , B2 i , B2 pure , CD34 pp.1362-1370
Published Date 2018/9/25
DOI https://doi.org/10.11477/mf.1403201479
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 Non-loop vessels(type B2)observed using narrow-band imaging magnified endoscopy(NBI-ME)were sub-classified into B2 i as thin vessels with high density and B2 pure as except for B2 i. The characteristics of B2 i and B2 pure were investigated.

 Fifty-three consecutive squamous cell carcinomas(SCC)in 51 patients treated by esophageal ESD from January 2011 to May 2018 enrolled in this retrospective study were assessed. Histological findings of the B2 area diagnosed by NBI-ME were investigated.

 All pathological diagnoses in 44 lesions that exhibited B2 pure were SCC. Pathological diagnoses of the 9 lesions that exhibited B2 i were SCC in 2 lesions and erosion or inflammation in 7 lesions.

 We investigated density and mean diameter of vessels in the regions that exhibited B2 i or B2 pure. Veins that were 100μm from the surface were counted using 22 sections stained by CD34.

 The mean density in B2 pure and B2 i was 3.35/mm and 8.22/mm, respectively(p=0.001). The mean minor axis of the vessels was 12.3μm and 6.65μm, respectively.(p=0.0028). B2 i has thin and high-density vessels, and B2 pure has thick and low-density vessels.

 B2 i is a characteristic finding of erosion or inflammation. Therefore, B2 i is an important parameter to prevent overdiagnosis of invasion depth.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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