Duodenal GIST, Presenting with an Anomalous Form, Report of a Case Makoto Sanomura 1 , Yuichi Sasaki 1 , Keisuke Yokohama 1 , Minori Hara 1 , Misa Kanaizumi 1 , Yasuhiro Ueda 1 , Hiroaki Yukami 1 , Yutaro Egashira 2 , Yoshinobu Hirose 2 , Hitoshi Nishitani 3 , Kazuhide Higuchi 3 1Department of Gastroenterology, Hokusetsu General Hospital, Takatsuki, Japan 2Department of Pathology, Osaka Medical College, Takatsuki, Japan 3Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Japan Keyword: GIST , 十二指腸 , 十二指腸球部 , 潰瘍 , イマチニブ pp.125-133
Published Date 2016/1/25
DOI https://doi.org/10.11477/mf.1403200532
  • Abstract
  • Look Inside
  • Reference
  • Cited by

 A 70s male with fever was admitted to our hospital for further investigation of multiple hepatic masses and duodenal tumors. The posterior wall of the duodenal bulb had a 3.5cm submucosal tumor-like mass, with a sharp 12mm periphery, deep isolated ulcers, and exposed tumor nodes in esophagogastroduodenoscopy. An anomalous gross morphology accompanied by a multihued ulceration and node was observed. The surroundings of the mass seemed compressed, suggesting an extraintestinal growth of the tumor. On the histopathological analysis of the biopsied tissue, GIST(gastrointestinal stromal tumor)was diagnosed. Multiple hepatic metastases of duodenal GISTs were observed, with direct invasion of the liver and pancreas. Thus, treatment with imatinib(400mg/day)was initiated.

Copyright © 2016, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院