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Long-term Outcome after ESD of Superficial Esophageal Squamous Cell Carcinoma Ryu Ishihara 1 , Takeshi Yamashina 1 , Kengo Nagai 1 , Noriko Matsuura 1 , Takashi Ito 1 , Fumi Matsui 1 , Mototsugu Fujii 1 , Noboru Hanaoka 1 , Sachiko Yamamoto 1 , Yoji Takeuchi 1 , Koji Higashino 1 , Noriya Uedo 1 , Hiroyasu Iishi 1 , Masaharu Tatsuta 1 , Yasuhiko Tomita 2 , Shingo Ishiguro 3 1Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan 2Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan 3PCL Osaka Pathology & Cytology Center, Ibaraki, Japan Keyword: 食道癌 , ESD , 予後 , リンパ節転移 , 内視鏡切除 pp.1263-1269
Published Date 2013/8/25
DOI https://doi.org/10.11477/mf.1403113914
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 Long-term outcomes after ESD(endoscopic submucosal dissection)of 208 patients with esophageal squamous cell carcinoma were analyzed. Out of 208 patients, 205 patients(98.6%)were treated with en bloc resection. Persistent recurrence was observed in 1 patient, metachronous cancer was observed in 25 patients and lymph node or spreading by metastasis was observed in 7 patients(1 with T1a-LPM cancer, 2 with T1a-MM ly1, v0 cancer, 4 with SM2 cancer). Metastasis developed in patients with T1a-MM ly1, v0 and SM2 cancer, although they were treated by additional treatment with chemoradiotherapy which prevents metastasis. Through follow-up, 9 patients died(3 due to esophageal cancer, 2 due to hypopharyngeal cancer, 1 due to pancreatic cancer, 2 due to pneumonia and 1 due to liver cirrhosis). The 3-year survival rates of patients with T1a-EP/LPM, T1a-MM/SM1 and SM2 cancer were 98.8%, 95.8% and 88.9%, respectively.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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