Clinical Course or Superficial Esophageal Cancer Treated by Endoscopic Submucosal Dissection Masaki Tanaka 1 , Hiroyuki Ono 1 , Kohei Takizawa 1 , Naomi Kakushima 1 , Kenichiro Imai 1 , Kinichi Hotta 1 , Hiroyuki Matsubayashi 1 1Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan Keyword: 食道癌 , ESD , 治療成績 , 偶発症 , 予後 pp.1253-1261
Published Date 2013/8/25
DOI https://doi.org/10.11477/mf.1403113913
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 Two hundred forty nine patients were observed in this study and treated from March 2005 to December 2011 in our cancer referral center. We classified them into 3 groups according to histological tumor depth(pT1a-EP and LPM, pT1a-MM and T1b-SM1, pT1b-SM2)and compared the treatment outcome(en bloc resection rate, R0 resection rate, complication, local recurrence, lymph-node metastasis, distant metastasis, and long term outcome). En bloc resection rates were 99.4%/100%/96.2%, perforation rates were 0.6%/3.3%/3.8%, and post-ESD stricture rates were 25%/37%/46%, respectively. With a median follow up period of 38 months, three-year cause specific survival rates were 100%/97.4%/100%. However, lymph-node metastasis rates were 0%/10.7%/7.7%, respectively. There were a few patients with lymph-node metastasis even after the curative resection such as pT1a-MM without lymhovasular invasion. Careful observation even after curative ESD is needed.

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