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NSAID-induced Small Bowel Ulcers Hiroki Endo 1 , Eiji Sakai 2 , Takuma Higurashi 2 , Hidenori Ohkubo 1 , Eiji Yamada 1 , Hiroshi Iida 2 , Takashi Nonaka 2 , Tomoko Koide 2 , Masahiko Inamori 2 , Hirokazu Takahashi 1 , Atsushi Nakajima 1 1Division of Endoscopy, Yokohama City University, School of Medicine, Yokohama, Japan 2Division of Gastroenterology, Yokohama City University, School of Medicine, Yokohama, Japan Keyword: カプセル内視鏡 , NSAID , 低用量アスピリン , 小腸潰瘍 , バルーン内視鏡 pp.457-463
Published Date 2013/4/25
DOI https://doi.org/10.11477/mf.1403113775
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 CE(capsule endoscopy)and double balloon enteroscopy are advanced modalities that now allow for full investigation of the entire small bowel. Especially, capsule endoscopic studies have revealed that NSAIDs(nonsteroidal anti-inflammatory drugs)including aspirin can cause a variety of abnormalities in the small bowel ; such as erosions, ulcerations, denuded areas and bleeding. Furthermore, use of NSAIDs can induce concentric membranous strictures, the so-called“diaphragm disease”, that can cause the retention of the capsule. Cessation of NSAID use is the best therapy for NSAID-induced ulcer in the small bowel. CE is very useful for diagnosis and evaluation of therapy for NSAID-induced enteropathy.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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