Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
- サイト内被引用 Cited by
要旨 カプセル内視鏡によって,NSAIDs起因性小腸粘膜傷害の現状が明らかになってきた.NSAIDsは,小腸にびらん,潰瘍,絨毛欠損や出血など多彩な病変を引き起こし,原因不明の消化管出血の一因となりうる.また,NSAIDs長期服用者においては,小腸に輪状潰瘍・膜様狭窄という特徴的な所見を来すことがあり,カプセル内視鏡検査に注意を要することがある.NSAIDs起因性小腸潰瘍に対しては休薬が確実な治療であるが,治療後の評価もカプセル内視鏡ならば,簡便かつ低侵襲で行うことが可能である.カプセル内視鏡はNSAIDs起因性小腸粘膜傷害の診断や治療評価に有用であると考えられる.
CE(capsule endoscopy)and double balloon enteroscopy are advanced modalities that now allow for full investigation of the entire small bowel. Especially, capsule endoscopic studies have revealed that NSAIDs(nonsteroidal anti-inflammatory drugs)including aspirin can cause a variety of abnormalities in the small bowel ; such as erosions, ulcerations, denuded areas and bleeding. Furthermore, use of NSAIDs can induce concentric membranous strictures, the so-called“diaphragm disease”, that can cause the retention of the capsule. Cessation of NSAID use is the best therapy for NSAID-induced ulcer in the small bowel. CE is very useful for diagnosis and evaluation of therapy for NSAID-induced enteropathy.
Copyright © 2013, Igaku-Shoin Ltd. All rights reserved.