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Eight Early Gastric Cancers, Report of a Case A. Imamura 1 , K. Kawasaki 2 1Department of Gastroenterology, National Sapporo Hospital 2Department of Surgery, National Sapporo Hospital pp.1049-1056
Published Date 1980/10/25
DOI https://doi.org/10.11477/mf.1403112812
  • Abstract
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 Eight Ⅱc type early gastric cancers, complicated with 2 atypical epithelium and a benign ulcer scar found in a 60 year-old man are reported.

 Cases of multiple early gastric cancers resected during the past 16 years in National Sapporo Hospital, are 20 among 305 cases of early gastric cancers (6.6 %). Therefore they are not so rare. But those with more multiple lesions are rare. Moreover, the more multiple and smaller they are, the more difficult they are to diagnose, although the method of detection of gastric cancers has markedly progressed.

 Before operation, 6 among 8 cancers were diagnosed by endoscopic biopsy in this patient. These cancer lesions had various measurements, from 5 mm to 15 mm in the maximum diameter.

 It is believed not so difficult to find the 2 overlooked lesions in resected gross specimen, which is the point to reflect.

 Microscopic appearance of cancers showed well differentiated adenocarcinomas in 7 lesions and moderately differentiated adenocarcinoma in another.

 The mucosa surrounding cancers showed intestinal metaplasia which had goblet cells almost without Paneth cells.

 Also was found epitheloid cell granuloma with infiltration of histiocytes, which was located in the mucosal and submucosal layer in the section of the most oral cancer (lesion No. 1). The cause of granuloma is not clear yet.

 This patient had been a heavy drinker and smoker. And his brothers died of gastric cancer and esophageal cancer respectively. In addition, such extrinsic or intrinsic factors possibly relate to the growth of cancer in this patient.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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