雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

A Case of Gastric Follicular Lymphoma (Nodular type) M. Kamijo 1 1Ikeda Municipal Hospital pp.961-967
Published Date 1977/7/25
DOI https://doi.org/10.11477/mf.1403112625
  • Abstract
  • Look Inside

 The patient was a 42 year-old male, who had been admitted because of epigastric pain during the gastric emptying time.

 The upper GI series showed numerous irregular and shallow ulcerous lesions accompanied with converging folds in an area of about 50×30 mm at the greater curvature side of the posterior wall of the middle corpus. Although the tip of each of the folds was enlarged, there was no definite sign of tapering nor moth-eaten appearance. And the gastric wall expanded well.

 Endoscopically, the thickened mucosal folds looked like cerebral gyri, and the lesion showed multiple erosions mixed with marked nodular protuberances, but no definite margin of Ⅱc can be seen. The biopsy specimens revealed no sure sign of malignancy.

 Gastrectomy was performed. No regional lymph node swelling was noted. In the excised specimen, multiple irregular ulcers were noted in the same area as was expected before. Although the tips of the convergent mucosal folds were enlarged and confluent, they were round and Ⅱc like lesion was not obvious. In addition, the mucosal surface showed partial nodular protuberance accompanied by bridging folds suspicious of submucosal tumor. From these findings, the ulcerous type of gastric lymphoma was highly suspected.

 Histologically, the neoplastic change was observed in the submucosal area forming a submucosal ulcer (Ul-Ⅱ type of Murakami's classification). In the mucosa where proper gastric glands were destructed, there were infiltrations of mature lymphocytes. The submucosa was occupied by enlarged lymph follicles differing in size with conspicuous germinal center.

and some follicles were fused with oneanother. Lymphoid cells and reticulum cells in the follicles showed prominent pleomorphism. From these histological findings, this case was diagnosed as follicular lymphoma, nodular (“follicular”) mixed type (lymphocytic and reticulum cell) by Rappaport's classification.

 It was fortunate that neoplastic tissue was limited to the submucosa and no signs of lymph node metastasis were observed. The prognosis is expected to be favorable.


Copyright © 1977, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

関連文献

もっと見る

文献を共有