Minute Carcinoma of the Esophagus with Synchronous Primary Carcinoma of the Hypopharynx, Report of Two Cases Wataru Takiyama 1 , Shigemitsu Takashima 1 , Minoru Morita 2 , Satoshi Koike 3 , Shosuke Moriwaki 4 1Department of Surgery, Shikoku Cancer Center Hospital 2Department of Radiology, Shikoku Cancer Center Hospital 3Department of Otolaryngology, Shikoku Cancer Center Hospital 4Department of Pathology, Shikoku Cancer Center Hospital pp.1123-1127
Published Date 1986/10/25
DOI https://doi.org/10.11477/mf.1403110180
  • Abstract
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 Two cases of minute carcinoma of the esophagus with synchronous primary carcinoma of the hypopharynx are presented. The subjects were men over 60 years of age, and each had a long-standing history of considerable cigarette and alcohol use. In both patients, lesions of the hypopharynx were found clinically prior to esophageal lesions. Despite the fact that they had no symptoms of swallowing disorder, esophageal investigations were performed. Esophagoscopy with Lugol's solution spraying method was able to demonstrate an esophageal lesion in one patient. The other patient could not be diagnosed clinically as having esophageal cancer. Histological examination confirmed the presence of squamous cell carcinomas of the esophagus in both cases. Two intramucosal tumors smaller than 3 mm were found in the first case, and two intraepithelial tumors smaller than 2 mm were found in the second case. These lesions were associated with dysplasia. Since there was no vascular invasion, they were considered as separate primaries rather than as case of metastasis.

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