Early Gastric Malignant Lymphoma Followed as Gastric Lymphoreticular Hyperplasia for Six and a Half Years, Report of a Case Shosuke Moriwaki 1 , Minoru Morita 2 , Ken Haruma 3,4 , Shigemitsu Takashima 5 1Department of Pathology, and Clinical Research Shikoku Cancer Center Hospital 2Department of Radiology, Shikoku Cancer Center Hospital 3Department of Pathology, Shikoku Cancer Center Hospital 4The Third Department of Intenial Medicine, Hiroshima University, School of Medicin 5Department of Surgery, Shikoku Cancer Center Hospital pp.71-76
Published Date 1985/1/25
DOI https://doi.org/10.11477/mf.1403109666
  • Abstract
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 A 68 year-old man, complaining of epigastralgia and melena, was referred to our hospital. He was diagnosed as having multiple gastric ulcers and scars by x-ray examination and endoscopy. Biopsy revealed lymphoreticular hyperplasia (LH). He was followedup under this diagnosis during six and a half years. but as he complained of augmentation of the subjective symptoms, he underwent 75% gastrectomy.

 Macroscopic findings of the surgical material showed superficial multiple ulcers and convergence of folds from the lesser curvature and oral region to ulcer scar.

 Histologically, mixture of LH and histiocytic malignant lymphoma was disclosed, and the degree of infiltration of the lymphoma was from the mucosa to submucosa. The ulcer was Ul‐Ⅲ.

 This is believed to be a rare case where malignant change of LH could be proved.

 The nature of LH is assumed to be specific local reactive gastritis due to autoimmune machanism, resembling Hashimoto's thyroiditis.

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