Cronkhite-Canada's Syndrome with Right Hemicolectomy and Subtotal Gastrectomy Performed in the Course of Six Years, Report of a Case M. Muratani 1 , T. Ogawa 1 , K. Sasamoto 1 , I. Aizawa 2 , G. Nakano 2 , T. Nakamura 2 1Department of Surgery, Saiseikai Maebashi Hospital 2The First Department of Surgery, School of Medicine, Gunma University pp.1367-1372
Published Date 1984/12/25
DOI https://doi.org/10.11477/mf.1403109531
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 A 54 year-old woman had been well until January 1977 when she developed atrophy of nails, hyperpigmentation of the extremities and hypoproteinemia. In July of the year, she had an acute onset of abdominal pain and was diagnosed as bowel obstruction in our hospital. Investigation in emergency laparotomy revealed invagination of the ileo-caecal region and diffuse polyposis of the stomach, small intestine and colon. Therefore, right hemicolectomy was performed. By histological examination of the resected colon, all polyps except an adenoma showed hyperplasia of non-atypical glands, cystic dilatation of glands and edematous stroma. She was given a high protein diet and plasma after the operation and was discharged in December of the year.

 In 1979, atrophy of nails was healed and gastric polyps were decreased in number. However, since 1980, the number and size of gastric polyps increased and severe hypoproteinemia appeared again.

 In February 1982, she was admitted to our hospital again because of anorexia and general fatigue. Roentgenographic and endoscopic examinations of the stomach revealed numerous diffuse polyps. It was assumed that severe hypoproteinemia was caused by the gastric polyps, and thus subtotal gastrectomy was performed. Histologically all polyps of the stomach were hyperplastic polyps.

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