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Concept on Early Cancer of the Ampulla of Vater Yoshifumi Ogura 1 , Toshizumi Imai 1 , Ryuji Mizumoto 1 1The First Department of Surgery, Mie University, School of Medicine pp.1079-1087
Published Date 1988/10/25
DOI https://doi.org/10.11477/mf.1403108623
  • Abstract
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 In order to better define early cancer of the ampulla of Vater, 67 cases in which the cancer of the ampulla of Vater was resected in our department were microscopically examined regarding, in particular, invasion of carcinoma within the muscle of Oddi (d0) . Patients with carcinoma of d0 were classified according to the following criteria: d0α is carcinoma restricted within the mucosa and d0β is carcinoma with invasion into but not beyond the muscle of Oddi.

 In case of d0α, neither lymphatic nor venous invasion was evident and no cancer death occurred after surgery. In case of d0β, although venous invasion was not found, lymphatic permeation was seen in 40% and lymph node metastasis in 20%. Prognosis, however, was favorable for this group; no recurrence of carcinoma after surgery. Furthermore, in cases with carcinoma extending beyond the boundary of the muscle of Oddi, prognosis was unfavorable, i.e., high rates of lymphatic permeation, venous invasion, perineural invasion and lymph node metastasis as well as high rate of recurrence after surgery.

 At present, therefore, early carcinoma of the ampulla of Vater may well be defined as carcinoma restricted within the muscle of Oddi.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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