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Two Cases of Primary Adenosquamous Carcinoma (Adenoacanthoma) of the Stomach T. Cho 1 , T. Yamaguchi 1 , A. Tanimura 1 , T. Sugimura 2 , J. Imamura 3 1The Second Department of Pathology, Kurume University, School of Medicine 2Department of Surgery, Almeida Hospital of Ooita City Medical Association 3Department of Surgery, Imamura Hospital pp.475-482
Published Date 1981/4/25
DOI https://doi.org/10.11477/mf.1403108023
  • Abstract
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 Two cases of primary adenosquamous carcinoma (adenoacanthoma) of the stomach, a 47 year-old male and a 69 year-old female, were reported.

 Adenoacanthoma of the stomach is a neoplasm of very rare occurrence, being reported only 90 cases including our two cases in Japan.

 Statistically, there is a peak of occurrence of gastric adenoacanthoma in 7th decade and the average of age is 57.5. It occurs more in males than in females at the ratio of 62 to 26. The highest incidence of the tumor location is in the pyloric region (50.0%).

 In both two cases of ours, adenocarcinomatous parts were seen mainly in the surrounding surface areas of the ulcer and squamous cell carcinomatous areas spread mainly in the ulcerous tissue, submucosa and in muscles. It would be suggested that the ulcer formation could be one of the causes inducing squamous metaplasia of adenocarcinoma.

 Our first case is the second report in Japan that was preoperatively diagnosed by the endoscopic biopsy.


Copyright © 1981, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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