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Japanese

A Fundamental Study of the Exocrine Pancreatic Function N. Ueda 1 , M. Namiki 1 13rd Department of Internal Medicine, Asahikawa Medical College pp.897-905
Published Date 1978/7/25
DOI https://doi.org/10.11477/mf.1403107365
  • Abstract
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 A comprehensive study on the exocrine pancreatic function and the clinical methods currently employed in this area has been made. Acetylcholine and cholecystokinin-pancreozymin act on acinar cells to not only secrete digestive enzymes, but to stimulate water and electrolytes secretion low in bicarbonate. Ca++ is necessary for the secretion of digestive enzymes; on the other hand, Na+ pump sensive to ouabain, is related to the secretion of water and electrolytes. Secretin acts on the duct cells to stimulate the secretion of water and electrolytes rich in bicarbonate. A small amount of digestive enzymes is also stimulated by secretion. The Na+ pump and the Na+ -K+ exchange system are thought to be related to the secretion of electrolytes. The action of secretion on the duct cells is mediated by cyclic AMP.

 The exocrine function of the pancreas shows great reserves; the normal range of the PS test has some latitude, so it is not always easy to distinguish abnormal results from normal ones when using this test.

 In this paper we have also described some of the procedures employed presently in the PS test at the clinical level, and we have pointed out some of the factors which may influence the results.


Copyright © 1978, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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