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Japanese

Histopatholoical Study on Tiny Iodine Unstained Lesions Smaller Than 5mm in Length Hideo Shimada 1 , Hiroyasu Makuuchi 1 , Takao Machimura 1 , Kyoichi Mizutani 1 , Koshi Kan-no 1 1The Second Department of Surgery, Tokai University, School of Medicine Keyword: ヨード不染帯 , ヨード染色 , 食道上皮内癌 pp.921-930
Published Date 1994/8/25
DOI https://doi.org/10.11477/mf.1403105885
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Eighty one of tiny iodine unstained lesions smaller than 5 mm in length from 14 patients with esophageal carcinoma were examined. These lesions were endoscopically observed and histopathologically evaluated on surgical specimens. Six lesions (7.4%) of squamous cell carcinoma. 10 lesions (12.3%) of dysplasia and the others were benign lesions. On the other hand, total of 305 lesions of esophageal biopsy specimens were taken from both 230 iodine unstained lesions smaller than 5 mm and 75 lesions up to 10 mm in length from 89 patients had no known esophageal cancer. Two lesions (0.9%) of carcinoma less than 5 mm, nine lesions (12.0%) of carcinoma up to 10 mm were discovered and found that the latter was apporoximatery 13 times higher of frequency. Dysplasia was respectively present in 65 lesions (28.3%) and in 21 lesions (28.0%) . There were no differences in frequency of size as for dysplasia. We thought that tiny iodine unstained lesions should be treated as follows. 1) If the unstained lesions were nearly 10 mm in length, only one biopsy should be taken from the center of these lesions. 2) If the unstained lesions were 5~8mm in length and strongly suspected carcinoma, we would like to propose endoscopic mucosal resection (EMR) rather than biopsy because biopsy not only make them unclear but also can not offer us a correct diagnosis on intraepitherial esophageal carcinoma of the basal layer type. 3) Observation of course is eligible for the lesions smaller than 5 mm in length.


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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