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要旨 CTE(CT enterography)は侵襲性が低く,Crohn病の初期診断および経過観察に有用な検査である.しかし,一方でCTEは縦走潰瘍や敷石像といった粘膜病変の描出能はX線造影検査や内視鏡検査に劣るとされている.今日ではCrohn病の治療は内視鏡的に診断されるmucosal healingに治療目標が置かれるようになりつつある.今後mucosal healingを目指していく治療戦略が主流となるとすれば,それを正しく評価できる,より低侵襲な検査法が重要となってくる.筆者らが現在取り組んでいるCTEにCAD(computer-aided diagnosis)技術を用いたCrohn病小腸画像診断について紹介する.
CTE(computed tomographic enterography)is a newer, relatively noninvasive enteric evaluation and may be suitable for diagnosis and follow-up for CD(Crohn's disease)patients. However, CTE is inferior to X-ray or endoscopy for precise diagnosis of intestinal mucosal lesions of CD patients such as longitudinal ulcer and/or cobble stone appearance. Nowadays, mucosal healing diagnosed by endoscopy is thought to be an important prognostic feature of the efficacy of treatment in CD. However, endoscopy is an invasive procedure and can lead to complications. Here, we introduce a navigation-based CAD(computer aided diagnosis)system for intestinal lesions in patients with CD.
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