Stomach and Intestine(Tokyo) Volume 35, Issue 5 (April 2000)

Peptic Ulcer Recurrence with Successful Eradication of Helicobacter pylori Yoshihiro Fukuda 1 , Issei Yamamoto 1 1The Fourth Department of Interal Medicine, Hyogo College of Medicine Keyword: H. pylori , 除菌 , 潰瘍再発 pp.620-622
Published Date 2000/4/25
  • Abstract
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 To evaluate the recurrence rate of gastric ulcer after eradication of H. pylori,282 gastric ulcer patients were followed-up over a period of five years.

 221patients were given therapy aimed at the eradication of H. pylori. 61 patients received acid-reducing conventional therapy.

 Six months after termination of treatment, it was found that 53 patients were conpletely free of H. pylori. During the next five years, three out of these 53 H. pylori-cured patients showed a relapse of gastric ulcer even though there was no reinfection with H. pylori.

 H. pylori eradication was unsuccessful in 168 cases and relapse of gastric ulcers was observed in 154 of these cases. Gastric ulcers also relapsed in 56 of the 61 patients that hadn't received H. pylori eradication treatment.

 It can safely be concluded that absence of H. pylori or successful H. pylori eradication prevents relapse in gastric ulcer patients.

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35巻5号 (2000年4月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院