Endoscopic Diagnosis of Colorectal Cancer and Dysplasia Associated with Ulcerative Colitis Kazuo Kusugami 1 , Yuji Nishio 1 , Kenji Ina 1 , Takafumi Ando 1 , Makoto Sugihara 2 1First Department of Internal Medicine, Nagoya University School of Medicine 2Department of Gastroenterology, Meitetsu Hospital Keyword: 潰瘍性大腸炎 , 早期癌 , dysplasia , surveillance , 高画素内視鏡 pp.937-943
Published Date 2002/6/25
DOI https://doi.org/10.11477/mf.1403104491
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 An increased risk of developing colorectal malignant lesions has been reported in patients with long-standing ulcerative colitis. In such patients, cancer surveillance is strongly recommended. High-resolution colonoscopy with magnifying observation is a useful method for detection of colorectal neoplastic lesions in such patients. Early carcinomas and dysplasia could be detected as flat elevated or plaque-like lesions with redness, discoloration, or surface irregularity. The pit structures obtained by magnifying observation in early carcinomas and dysplasia associated with ulcerative colitis are almost similar to those observed in ordinary colorectal neoplastic lesions. Given the inconspicuous endoscopic features of these early lesions, endoscopists should be aware of minimal changes in the mucosa during colonoscopic examination and consider magnifying observation with a dye spraying method.

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