Study on Endoscopic Diagnosis of Dysplasia and Colitic Cancer: Significance of Magnifying Endoscopic Diagnosis Masahiro Igarashi 1 , Miwa Sada 1 , Kiyonori Kobayashi 1 , Shigeru Yoshizawa 1 , Tomoe Katsumata 1 1Department of Internal Medicine, Kitasato University East Hospital Keyword: ulcerative colitis , dysplasia , colitic cancer , magnifying endoscopy pp.925-935
Published Date 2002/6/25
DOI https://doi.org/10.11477/mf.1403104489
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 We focused our study on the diagnosis by endoscopic examination of dysplasia and colitic cancer associated with ulcerative colitis. In all, there were 22 subjects which included 13 patients with dysplasia only ; 3 patients in whom dysplasia was observed previously to the detection of colitic cancer ; and 6 patients with colitic cancer only. Characteristics of findings of dysplasia were nodules with granular lesions (9 cases), flat elevated lesions (4 cases) and flat mucosa (3 cases) . Various early colitic cancers such as Ⅱc, Ⅱa, Ⅰs, Ⅰsp and nodule-aggregating tumor-like lesions were seen. Advanced colitic cancers were often observed to be strongly infiltrating. Magnifying observation with dye spraying was useful for the detection or diagnosis of dysplasia and colitic cancer associated with ulcerative colitis. The main pit patterns of dysplasia or early colitic cancer were type Ⅳ and type Ⅲs with ⅢL.

 It is concluded that magnifying observation with dye spraying is effective for the detection of dysplasia or colitic cancer associated with ulcerative colitis.

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