Malignant Fibrous Histiocytoma (MFH) of the Stomach, Report of a Case Kunio Takagi 1 , Keiji Iwakiri 1 , Hiroshi Matsunaga 1 1Hayashi Surgical Hospital Keyword: 胃悪性線維性組織球腫 pp.1769-1775
Published Date 1998/12/25
DOI https://doi.org/10.11477/mf.1403103899
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 A 66-year-old female was admitted because of severe anemia. X-ray and endoscopic examinations disclosed a submucosal tumor with a central protruded lesion on the posterior wall of the gastric body. Distal gastectomy was performed. The resected specimen revealed a unique protrusion, measuring 4×4.5×7.5 cm. Histologically, the lesion mainly occupied the submucosa and reached to the subserosa and was composed of atypical fibroblasts and atypical cells with bizarre giant nuclei, and diagnosed as malignant fibrous histiocytoma (MFH).

 Six cases of MFH were reviewed, and the gross findings were submucosal tumor, protruded lesion and ulcerated lesion. The gross finding of this case was glands penis-like appearance, and this unique gross finding is special for inflammatory fibroid polyps, but is also recognized in cases of MFH. Many cases of MFH showed clinically severe anemia due to bleeding from the tumor and, in this case, the cause of bleeding was discussed. The prognosis of MFH cases were poor due to the far-advanced nature of the tumors, but the prognosis in this case is good due to the fact that it was an intra-gastric tumor.

Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.


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