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Regression of Mucosa-associated Lymphoid-tissue (MALT) Lymphoma of the Rectum after Eradication of Helicobacter pylori, Report of a Case Fumihiko Inoue 1 , Katsumi Azuma 1 , Osamu Nishida 1 , Takashi Mizumoto 1 , Tatsuyoshi Saiga 2 1Department of Gastroenterology, Ohtsu Red Cross Hospital 2Department of Pathology, Ohtsu Red Cross Hospital Keyword: Helicobacter pytori , 除菌療法 , 直腸MALTリンパ腫 pp.1683-1686
Published Date 2001/12/25
DOI https://doi.org/10.11477/mf.1403103394
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 We report a case of mucosa-associated lymphoid-tissue lymphoma of the rectum that regressed after eradication of Helicobacter pylori. A 67-year-old female was admitted to our hospital for further examination of a rectal polypoid lesion. Colonoscopic examination revealed a broad-based protrusion in the rectum (Rb) resembling a submucosal tumor. Histopathological examination of biopsy specimens showed diffuse infiltration of centrocyte-like cells, which were positive for L26 immunostaining and also formed lymphoepithelial lesions. Southern blot analysis of the specimen detected gene rearrangement of immunoglobulin heavy-chain (IgH). H. pylori was shown to be positive by rapidurease test, culture, and histological examination of biopsied gastric mucosa. Eradication therapy for H. pylori was successfully carried out. Colonoscopic examination 6 weeks after the end of the treatment showed marked regression of the rectal tumor. Almost complete regression was further confirmed by colonoscopy 33 weeks after the treatment.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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