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Japanese

Regression of Mucosa-Associated Lymphoid Tissue Lymphoma of the Ascending Colon after Helicobacter Pylori Eradication Therapy Toshiki Mimura 1,2 , Masaki Kawahara 2 , Michio Kaminishi 2 , Keiji Matsuda 1 , Miki Adachi 1 , Kota Okinaga 1 1Department of Surgery, Teikyo University School of Medicine 2Department of Gastrointestinal Surgery, University of Tokyo Keyword: 大腸MALTリンパ腫 , Helicobacter pylori , 除菌療法 pp.363-371
Published Date 2006/3/25
DOI https://doi.org/10.11477/mf.1403100292
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 A 68-year-old man was admitted to our department for the treatment of a sigmoid colon polyp diagnosed by a colonoscopic examination performed on account of positive fecal occult blood test. When the polyp was endoscopically resected, a submucosal tumor of 2 cm in diameter was incidentally found in the ascending colon. Histological examination of the biopsy specimens and polymerase chain reaction analysis of the immunoglobulin heavy chain rearrangement revealed that the tumor was a mucosa-associated lymphoid tissue lymphoma (MALT lymphoma). Based on a report that rectal MALT lymphoma regressed with H. pylori eradication therapy, the eradication therapy was attempted on this patient partially because he was not fit and well. His stomach was positive for H. pylori infection. One month after the therapy, the eradication proved successful and a colonoscopic examination demonstrated that the MALT lymphoma had remarkably regressed into 3 nodules each of which was 3~4mm in diameter. On colonoscopy 8 months after the therapy, the tumor had disappeared. Including this patient, 17 cases of colorectal MALT lymphoma have been reported so far that have regressed after H. pylori eradication therapy.


Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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