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Elevated and Depressed Lesions of the Esophago-gastric Junction Masashi Ono 1,2 , Satoko Morohashi 1 , Fuyuki Sato 1 , Hiroko Seino 1 , Toru Yoshikawa 1,3 , Hiroshi Ogasawara 1,3 , Kaori Takasugi 1,4 , Yoshinori Igarashi 2 , Hiroshi Kijima 1 1Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine, Hirosaki, Japan 2Department of Gastroenterology, Toho University Medical Center Omori Hospital, Tokyo 3Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan 4Department of Gastroenterology and Hematology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan Keyword: 食道胃接合部 , 隆起性病変 , 陥凹性病変 , 炎症性ポリープ , Barrett食道 pp.1155-1166
Published Date 2011/7/25
DOI https://doi.org/10.11477/mf.1403102301
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 Early lesions of the EGJ(esophagogastric junction)were analyzed morphologically. We examined 172 cases of surgically resected esophagus due to the esophageal cancers, and found 24 early lesions of the EGJ. The 24 lesions were divided into the two groups : i.e. elevated and depressed lesions.

 The elevated lesions included epithelial hyperplasia, inflammatory changes, and Barrett's esophagus mucosa. The epithelial hyperplasia showed thickened stratified squamous epithelium or columnar epithelial hyperplasia. The former was thought to be early lesions of squamous papilloma. The columnar epithelial hyperplasia and inflammatory changes were thought to include early lesions of inflammatory polyps.

 The depressed lesions included Barrett's esophagus mucosa, hyperplasia of the surrounding epithelium, and ulcerative lesions. Barrett's mucosa in the present study may develop to become the clinical SSBE(short segment Barrett esophagus). The hyperplasia of the surrounding epithelium and ulcerative lesions resulted in the relative depressive lesions of EGJ.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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