Diagnostic Performance and Limitations of Magnifying Narrow-Band Imaging for the Diagnosis of Minute Gastric Cancer Kenshi Yao 1 , Shoko Fujiwara 1 , Takashi Nagahama 2 , Takao Kanemitsu 2 , Motochika Yasaka 2 , Yasuhiro Takaki 2 , Toshiyuki Matsui 2 , Hiroshi Tanabe 3 , Kentaro Imamura 3 , Akinori Iwashita 3 1Department of Endoscopy, Fukuoka University Chikushi Hospital, Chikushino, Japan 2Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan 3Department of Pathology, Fukuoka University Chikushi Hospital, Chikushino, Japan Keyword: 微小胃癌 , 拡大内視鏡 , narrow band imaging , 診断能 , 限界 pp.843-856
Published Date 2013/5/25
DOI https://doi.org/10.11477/mf.1403113835
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 Objectives : We investigated the diagnostic performance of M-NBI(magnifying narrow-band imaging)and conventional white-light imaging and determined limitations of M-NBI.

 Methods : Consecutive minute lesions no more than 5mm were included in this study. The primary endpoint was sensitivity, the secondary endpoints were specificity and overall accuracy for both M-NBI and C-WLI(conventional white-light imaging). In order to determine the limitations, we reviewed clinical and pathological reports of the misdiagnosed lesions.

 Results : Overall, 129 lesions(36 cancers and 93 non-cancer lesions)were included in the study. The sensitivity of C-WLI vs. M-NBI was 41.0%(24.9~57.1%)vs. 75.0%(95% CI : 61.4~88.6%), respectively. The specificity and the accuracy were 82.0%(74.2~89.8%)vs. 91.0%(85.2~96.8%)and 71.0%(63.2~78.8%)vs. 87.0%(81.2~92.8%), respectively. The most significant misdiagnosis of M-NBI were due to artifacts caused by previous biopsies, limitations of criteria and interpretation errors.

 Conclusion : The sensitivity and the accuracy of M-NBI is superior to those of C-WLI although M-NBI has limitations in exceptional cases.

Copyright © 2013, Igaku-Shoin Ltd. All rights reserved.


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