Japanese

Usefulness of Magnifying Endoscopy with Narrow-band Imaging for Determining the Margins of Superficial Flat Type(0IIb)of Early Gastric Carcinomas Kenshi Yao 1 , Takashi Nagahama 2 , Shinichiro Maki 2 , Masao Takeichi 2 , Yasuhiro Takaki 2 , Fumihito Hirai 2 , Toshiyuki Matsui 2 , Hiroshi Tanabe 3 , Nobuaki Nishimata 3 , Atsuko Ohta 3 , Seiji Haraoka 3 , Akinori Iwashita 3 1Department of Endoscopy, Fukuoka University Chikushi Hospital, Chikushino, Japan 2Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino, Japan 3Department of Pathology, Fukuoka University Chikushi Hospital, Chikushino, Japan Keyword: 早期胃癌 , 拡大内視鏡 , NBI(narrow band imaging) , 進展範囲度診断 , 0IIb pp.86-100
Published Date 2010/1/25
DOI https://doi.org/10.11477/mf.1403101837
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 Background & aims : Superficial flat type(IIb)of early gastric carcinoma or accompanied IIb lesions are used to a limitation of diagnosis by standard endoscopy alone. We investigated usefulness of magnifying endoscopy(ME)with narrow-band imaging(NBI)for determining the margins of such flat carcinomas. 

 Materials and methods : Consecutive 425 early gastric carcinomas, which had been resected by ESD, were included to this study. We studied the following subjects.(1)The prevalence of the carcinomas according to the macroscopic types whose margins were clear vs. unclear by standard endoscopy alone.(2)The usefulness and limitations of ME with NBI for determining of the margins of the carcinomas according to the macroscopic types, which showed unclear margins by standard endoscopy.(3)Histological characteristic for limitations of ME with NBI.

 Results :(1)Overall, the prevalence of the lesions, which showed unclear margins by standard endoscopy, was nearly 20%. IIb and accompanied IIb lesions were still limitations of standard endoscopy.(2)For 76% of such leisions, ME with NBI was useful for determining the margins of the carcinoma irrespective of macroscopic type such as IIb.(3)The histological characteristic for the difficult lesions were mainly poorly differentiated adenocarcinoma and partly moderately- or very well-differentiated adenocarcinoma.

 Conclusions : ME with NBI enables endoscopist to determine the margins of carcinoma even in IIb or accompanied IIb lesions.


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