Regression of Benign Lymphoid Polyposis of the Rectum with Detection of Immunoglobulin Heavy Chain Gene Rearrangement after Eradication of Helicobacter pylori, Report of a Case Sei Kurokawa 1 , Akimichi Imamura 1 , Tomonori Anbo 1 , Satoshi Motoya 1 , Hiroshi Kozawa 1 , Satoshi Maeda 1 , Takeshi Hagiwara 1 , Shinji Yoshii 1 , Hitoshi Nishioka 1 , Hiroki Tanaka 1 , Toshihiro Sato 2 , Kiyoto Natsui 3 1Division of Gastroenterology, Sapporo Kosei General Hospital 2Keiyukai Institute of Clinical Pathology 3Natsui Gastroenterology and Internal Medicine Clinic Keyword: 直腸 , リンパ濾胞性ポリポーシス , IgH遺伝子再構成 , H. pylori除菌療法 pp.409-414
Published Date 2006/3/25
DOI https://doi.org/10.11477/mf.1403100298
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 A 60's woman was introduced to our hospital for further examination concerning positive fecal occult blood. Double contrast study of the lower rectum showed a lot of hemispheric polypoid lesions with smooth surface. Colonoscopy revealed many submucosal tumors in the rectum, measuring 6 mm in diameter. The resected specimen by EMR showed proliferation of normal lymphocytes forming lymph follicles. Although there was detection of immunoglobulin heavy chain gene rearrangement by polymerase chain reaction, the lesions were diagnosed as benign lymphoid polyposis of the rectum.

 The patient was negative for H. pylori, but we performed eradication of H. pylori. We proved the disappearance of the lymphoid polyposis by colonoscopy.

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