Type IIc+IIa(Superficial Depressed Type)Intramucosal Endocrine Cell Carcinoma of the Rectum, Report of a Case Sei Kurokawa 1 , Akimichi Imamura 1 , Shunji Muraoka 2 1Division of Gastroenterology, Sapporo Kosei General Hospital 2Division of Clinical Pathology, Sapporo Kosei General Hospital Keyword: 内分泌細胞癌 , 直腸 , 粘膜内癌 , 拡大内視鏡 pp.1547-1554
Published Date 2004/10/25
DOI https://doi.org/10.11477/mf.1403100591
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 A62-year-old man visited our hospital for further examination concerning positive fecal occult blood in December,2001. Colonoscopy revealed a Type IIc+IIa(a depressed type)lesion in the rectum, measuring11mmin its largest diameter. The surface of the depressed area mostly appeared to be regenerating non-neoplastic mucosa, with signs of tumorous mucosa in part. The biopsy specimen of this lesion was diagnosed as endocrine cell carcinoma. Low anterior resection was performed. This case is a very rare case presenting intramucosal endocrine cell carcinoma, with no component of adenocarcinoma and showing proliferation of tumor cells by overexpression of p53protein and staining for Ki-67.

 For this reason, the case was thought to be noteworthy for supplying information concerning the development of endocrine cell carcinoma.

 1) Division of Gastroenterology, Sapporo Kosei General Hospital, Sapporo, Japan

 2) Division of Clinical Pathology, Sapporo Kosei General Hospital, Sapporo, Japan

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