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Gastric Adenocarcinoma of “Crawling Type”, its Clinicopathological Characteristics and Implications for Diagnosis and Treatment Hiroshi Kawachi 1 , Naoko Okamoto 1 , Tatsuya Yoshida 2 , Takashi Ito 1 , Eisaku Ito 1 , Kazuyuki Kojima 3,4 , Tatsuyuki Kawano 3 , Kenichi Sugihara 4 , Toichiro Takizawa 5 , Yoshinobu Eishi 1 1Department of Human Pathology, Tokyo Medical and Dental University, Tokyo 2Department of Surgery, Kudanzaka Hospital, Tokyo 3Department of Esophagogastric Surgery, Tokyo Medical and Dental University, Tokyo 4Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 5Department of Molecular Pathophysiology, Tokyo Medical and Dental University, Tokyo Keyword: 低異型度胃癌 , 横這型胃癌 , 手つなぎ型腺管癌 , WHYX lesion , 印環細胞癌 pp.1203-1211
Published Date 2010/6/25
DOI https://doi.org/10.11477/mf.1403101975
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 Clinicopathological implications of so-called “crawling-type" gastric adenocarcinoma was shown in the study. Frequency was only 1.7%(10/575)of examined pT1a(M)and pT1b1(SM1)cancer. Macroscopically, 0-IIc-type was predominant and 0-IIb-component often co-existed resulting in an unclear border. Histological characteristics were as follows :(1)Cancer cells showing low-grade cellular atypia,(2)mainly composed of irregularly branched/fused glands and cystic dilated glands with slightly eosinophilic cytoplasm,(3)co-existing with minor foci of signet ring cells,(4)low glandular-stromal ratio,(5)cancer glands occupying mainly the neck zone of the mucosa. Recognition of this type of cancer is essential for both clinicians and pathologists for appropriate diagnosis and treatment.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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