Endoscopic Diagnosis of Tissue Atypia Using Newly Developed Single-lens Ultra-high Magnifying Endoscopy Haruhiro Inoue 1 , Hitomi Minami 1 , Makoto Kaga 1 , Yoshitaka Sato 1 , Satoshi Sugaya 1 , Shin-ei Kudo 1 1Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan Keyword: 超・拡大内視鏡 , エンドサイト , 内視鏡的異型度診断 , IPCL , ECA分類 pp.1689-1695
Published Date 2009/10/25
DOI https://doi.org/10.11477/mf.1403101777
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 Single-lens ultra-high magnifying endoscopy which allows continuous observation from the regular endoscopic image to ultra-high magnification image was newly developed by cooperation between Olympus and the authors. By regular endoscopy, a lesion is identified as a brownish area using NBI image enhancement. Standard magnifying view enables the observer to demonstrate the IPCL pattern of the lesion. In a reported case the lesion was identified as IPCL type IV, which arouses suspicion of high grade intraepithelial neoplasia. The ultrahigh magnifying view(endocytoscopy)revealed ECA-3 which often corresponds to low grade intraepithelial neoplasia. Histological diagnosis for the resected specimen was low grade intraepithelial neoplasia. Its image is similar to the endocytoscopic image. As in this case, the newly designed ultra-high magnifying endoscopy enables endoscopic evaluation of tissue atypia by evaluating both structural atypia and cellular atypia.

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