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Endoscopic Diagnosis of Tissue Atypia (EA) in the Esophageal Squamous Epithelium―IPCL Pattern Classification and ECA Classification Haruhiro Inoue 1 , Makoto Kaga 1 , Yoshitaka Sato 1 , Satoshi Sugaya 1 , Kunihiko Wakamura 1 , Hitoshi Satodate 1 , Shin-ei Kudo 1 , Shigeharu Hamatani 2 1Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan 2Department of Pathology, Showa University Northern Yokohama Hospital, Yokohama, Japan Keyword: 食道dysplasia , 食道異形成 , IPCLパターン分類 , ECA分類 , endocytoscopic atypia classification pp.161-171
Published Date 2007/2/25
DOI https://doi.org/10.11477/mf.1403100946
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 Standard magnifying endoscopy has approximately 100 fold magnifying power. IPCL (intraepithelial papillary capillary loop) pattern is diagnosed by utlizing it. NBI (narrow band imaging system) is extremely useful to effectively recognize IPCL as a brown spot. In IPCL type classification, type I mainly includes normal epithelium. Type II corresponds to inflammatory change or non-neoplastic tissue and type III reflects border line lesions. Type IV strongly suggests carcinoma in situ. Type V-1 is definitely diagnosed as carcinoma.

 Endocytoscopy has approximately 500 fold magnification, which enables us to observe cells and cell nuclei. Endocytoscopic images are classified into five categories from normal epithelium to malignant tissue as ECA classification (endocytoscopic diagnosis of tissue atypism classification). ECA-III should be closely followed up. ECA IV and V are considered to need treatment in a clinical setting.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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