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Clinicopathlogical Features of Gastric Cancer Detected after Helicobacter Pylori Eradication : Results from 100 Cases of Gastric Cancer in a Multi-center Study Tomoari Kamada 1 , Katsuhiro Mabe 2 , Kazutoshi Fukase 3 , Kazuhiko Inoue 4 , Hiroyuki Okada 5 , Taiji Matsuo 6 , Masanori Ito 6 , Kenji Tokumo 7 , Keitaro Kobatake 8 , Yumi Sato 9 , Akiko Shiotani 1 , Jiro Hata 10 , Yuzuru Kawamura 11 , Shinji Tanaka 12 , Takashi Akiyama 13 , Ken Haruma 1 1Department of Internal Medicine, Division of Gastroenterology, Kawasaki Medical School, Kurashiki, Japan 2Division of Gastroenterology, KKR Sapporo Medical Center, Sapporo, Japan 3Department of Internal Medicine, Yamagata Prefectural Central Hospital, Yamagata, Japan. 4Department of General Medicine, Matsue Red Cross Hospital, Matsue, Japan 5Division of Gastroenterology, Okayama University Graduate School of Medicine, Okayama, Japan 6Department of Medicine and Molecular Science, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan 7Tokumo Clinic, Fukuyama, Japan 8Kobatake Hospital, Fukuyama, Japan 9Department of Human Dry Dock, Health Care Center, Kawasaki Hospital, Kurashiki, Japan 10Division of Endoscopy and Ultrasonography, Kawasaki Medical School, Kurashiki, Japan 11Kawamura Hospital, Hiroshima, Japan 12Department of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan 13Division of Pathology, Kawasaki Medical School, Kurashiki, Japan Keyword: Helicobacter pylori感染 , 除菌 , 胃癌 pp.1810-1819
Published Date 2008/11/25
DOI https://doi.org/10.11477/mf.1403101517
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 Eradication of H. pylori is expected to prevent the development of gastric cancer. However, gastric cancer is sometimes discovered after successful eradication of H. pylori. We investigated the clinicopathlogical features of 100 gastric cancer patients detected after successful H. pylori eradication in a multi-center study. Gastric cancers discovered after H. pylori eradication were characterized as early non-cardiac cancers of the intestinal type with ulceration and corporal atrophic gastritis. Our study revealed that careful follow-up endoscopic examination for possible gastric cancer is necessary even after successful H. pylori eradication in patients with gastric ulcer or early gastric cancer after endoscopic resection, because such patients may have baseline mucosal atrophy in the corpus


Copyright © 2008, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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