Gastric Wall Metastasis from a Renal Cell Carcinoma 8 years After Radical Nephrectomy, Report of a Case Mutsuhiro Hara 1 , Shinji Tanaka 1 1Department of Endoscopy, Hiroshima University Hospital Keyword: 転移性胃癌 , 腎細胞癌 , 内視鏡的切除術 pp.1839-1844
Published Date 2003/12/25
DOI https://doi.org/10.11477/mf.1403100712
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 Metastasis of any cancer to the stomach is quite uncommon. Gastric metastasis from renal cell carcinoma, in particular, is extremely rare and is usually discovered at autopsy. Recently, we treated a case of gastric metastasis from a renal cell carcinoma that manifested itself 8 years after radical nephrectomy. In 1993, a 69-year-old man was diagnosed with a right renal cell carcinoma and underwent curative nephrectomy followed by postoperative interferon therapy. In 1998, 1999 and 2000, pulmonary metastases were identified and treated each time by partial lung resection. In May 2001, the patient visited a neighborhood clinic for heartburn. An x-ray examination showed a polypoid lesion in the posterior wall of the middle gastric body. The patient was referred to our hospital, where gastrointestinal endoscopy showed a solitary polypoid lesion about 15 mm in diameter located in the greater curvature of the middle gastric body. Microscopic examination of a biopsy specimen indicated that the lesion was an adenocarcinoma, and submucosal invasion was detected by endoscopic ultrasonography. Endoscopic resection was performed, and histologic examination of the resected specimen confirmed a diagnosis of clear cell renal carcinoma. Histologic similarity between this lesion and the primary tumor and lung metastases led us to consider it an exceedingly rare late recurrence to the gastric wall. Although the location was unusual in this case, late recurrence is characteristic of renal cell carcinoma, so careful long-term follow-up is needed.

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