Japanese

Large Gastrointestinal Stromal Tumor of the Small Intestine, Report of a Case Shinichiro Yada 1 1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University Keyword: 小腸 , c-kit , CD34 , gastrointestinal stromal tumor(GIST) , 小腸 X 線検査 pp.695-699
Published Date 2004/4/24
DOI https://doi.org/10.11477/mf.1403100510
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 A47-year-old man was admitted to our hospital because of lower abdominal pain. Abdominal ultrasonography, computed tomography and magnetic resonance imaging revealed a large, multi-cystic tumor in the left lower abdomen. Double-contrast radiography of the small intestine showed a fistulous barium fleck in a torturous and stenotic segment of the ileum. Macroscopically, there was an extrinsic ileal mass measuring14cm in its largest diameter. Because of the large size of the tumor, the ileal segment was strangulated. Histological examination revealed the tumor to be composed of spindle cells having high cellularity and frequent mitotic figures. The tumor cells were positive for c-kit and CD34. They were also positive for α-SMA and negative for S-100protein.

 Based on these finding, the tumor was diagnosed as a malignant gastrointestinal stromal tumor of the smooth muscle type.

 1) Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan


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