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要旨●0-IIc陥凹型早期大腸癌は,小径でも粘膜下層(SM)浸潤やリンパ節転移を来しうる高リスク病変である.今回筆者らは,便潜血陽性を契機に発見された横行結腸10mm大0-IIa+IIc陥凹型T1b癌を経験した.周囲に皺襞集中を認め,NBI拡大観察でJNET分類Type 3,色素拡大でVI型高度不整と限局したVN型pitを認めcT1bと診断したが,患者希望によりEMRを施行した.病理組織学的所見でSM浸潤距離1,560μmと静脈侵襲陽性を示し追加腸切除を行った.本稿では,本症例を通じて,陥凹型病変では腫瘍径のみで治療適応を決めず,non-polypoid・de novo carcinomaを念頭に通常観察と拡大観察を総合して深達度を評価すべきことを示す.
Depressed-type early colorectal cancer can be a high-risk lesion, even when it is small, because it may show submucosal invasion and lymph node metastasis. We encountered a 10mm 0-IIa+IIc depressed-type lesion in the transverse colon detected by positive fecal occult blood testing. Converging folds were seen around the lesion. Magnifying narrow-band imaging revealed Japan NBI Expert Team(JNET)type 3, and chromoendoscopy with crystal violet showed severely irregular-type VI pits with a focal VN pit pattern, resulting in a diagnosis of clinical T1b cancer. Despite recommending surgery, endoscopic mucosal resection was performed at the patient's request. Pathology revealed pT1b cancer with venous invasion, and additional segmental colectomy was performed. This case suggests that the choice of treatment for depressed lesions should not be based on lesion size alone ; rather, they should be regarded as non-polypoid de novo malignancies, and invasion depth should be assessed comprehensively by combining conventional and magnifying endoscopic findings.

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