結節性紅斑を伴った真性多血症

・真性多血症に対し内服していたヒドロキシカルバミドを自己減量後に発症した，下腿の結節性紅斑を経験した．・安静とヒドロキシカルバミドの増量，プレドニゾロン内服により症状はいったん軽快したが，血液粘度の増加に相関して皮疹が増悪した．（「症例のポイント」より）

A case of polycythemia vera with erythema nodosum Tsutsumi, Midori1）Nakamura, Misa1）Ito, Takamichi2）Furue, Masutaka2） 1）Division of Dermatology, Haradoi Hospital 2）Department of Dermatology, Graduate School of Medical Sciences, Kyushu University Abstract An 80-year-old woman with polycythemia vera presented to our department because of many subcutaneous nodules in her both legs. Histopathologically, there were septal and lobular panniculitis. After excluding nodular vasculitis, sarcoidosis and Behcet's disease by blood test, microbial culture, and radiologic and ophthalmologic examination, we established a diagnosis of erythema nodosum. These nodules were relieved by oral corticosteroid, but they repeatedly recurred during the tapering of the corticosteroid. The nodules were exacerbated in parallel with increased blood viscosity due to polycythemia vera. Erythema nodosum may be included as a skin manifestation of polycythemia vera.