2．血液透析患者の末梢白血球中の好中球/リンパ球比と精神・行動特性との関係

The relation between the neutrophil and lymphocyte ratio in leukocytes and the psychological processes and behavioral characteristics in patients with hemodialysis

　本研究の目的は，血液透析患者の好中球，リンパ球比と体重増加率，心理，精神・行動特性との関連について明らかにすることである．研究参加に同意の得られた外来血液透析患者28名（非糖尿病患者14名，糖尿病患者14名）を対象とした．分析は，好中球，リンパ球比および体重増加率は臨床検査データを用い，心理，精神・行動特性ついてはSDS，STAI，自己抑制度，感情認知困難度を用いた．結果，非DM群は体重増加率，SDS得点，STAI得点と有意な正の相関関係が認められた．一方DM群は，N/L比と体重増加率，SDS，STAI，自己抑制度，感情認知困難度のいずれの項目とも関連が認められなかった．N/L比は，非DM群のストレス状態の指標となることが示唆された．

　The purpose of this study is to clear the relationship between the neutrophil and lymphocyte ratio and weight gain rate and behavioral characteristics and psychological processes in hemodialysis patients. The subject were 28 hemodialysis outpatients (non diabetic group 14, diabetic group 14) who agreed to participate in this study. Blood data and weight gain rate were used to measure the degree of clinical inspection data. In order to assess the psychology, STAI, SDS, difficulty in emotion recognition scale, the self-repressiveness scale was used. A result of correlation analysis indicated that non diabetic group relation between the neutrophil and lymphocyte ratio, and depression, anxiety, and weight gain rate was significant. The diabetic group was not relation between the neutrophil and lymphocyte ratio, and all the items. These results suggest that observation of the neutrophil and lymphocyte ratio can be used as an indicator of the mental state of non diabetic group.