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Ulcerative Colitis in Remission with Cerebral Abscess and Septic Pulmonary Emboli:A Case Report Takahiro YAMAUCHI 1 , Hirotoshi KATSUMURA 1 , Yoshiyuki NOGUCHI 1 , Ken-ichiro KIKUTA 2 1Department of Neurosurgery, Nakamura Hospital 2Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui Keyword: brain abscess , ulcerative colitis , pulmonary embolism , septic pulmonary emboli pp.1099-1104
Published Date 2013/12/10
DOI https://doi.org/10.11477/mf.1436102136

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 A 69-year-old man with a 4-year history of ulcerative colitis(UC)presented at our hospital with high fever, dysarthria, and right hemiparesis. Computed tomography(CT)of the head revealed a low-density area in the left temporal lobe. Chest CT exposed multiple pulmonary nodules in his right lung. Gadolinium-enhanced magnetic resonance imaging(MRI)indicated a 3-cm tumor with ring enhancement located in the left temporal lobe. The patient was diagnosed with a brain abscess and septic pulmonary emboli(SPE);antibiotic therapy was initiated. Shrinkage of the brain abscess was not observed in a follow-up MRI;thus, he underwent aspiration and drainage of the abscess 11 days after his hospitalization. Intravenous antibiotic therapy was continued for 6 weeks after the operation. Follow-up chest CT performed 48 days after his hospitalization revealed disappearance of the SPE. Follow-up head MRI conducted 63 days after his hospitalization indicated that the cyst had almost disappeared. Occurrence of a brain abscess in patients with UC has been very rarely reported in Japan. To the best of our knowledge, this is the first report of a case of a brain abscess in conjunction with UC and SPE. It is believed that patients with UC have compromised immunity and exhibit activation of the blood coagulation system. Our report suggests that medical practitioners should consider the possibility of a brain abscess and SPE for patients with UC.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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